重症监护病房患者外周灌注指数的分布特征及影响因素分析

doi:10.16352/j.issn.1001-6325.2026.10.1414

基础医学与临床 ›› 2026, Vol. 46 ›› Issue (10): 1414-1418.doi: 10.16352/j.issn.1001-6325.2026.10.1414

重症监护病房患者外周灌注指数的分布特征及影响因素分析

方宁¹, 赵明曦¹, 岳雯静², 柳馨怡³, 姜淼¹, 范丽祎¹, 罗红波^1*

中国医学科学院北京协和医学院北京协和医院 1.重症医学科;2.护理部,北京 100730;
3.中国医学科学院北京协和医学院护理学院,北京 100144

收稿日期:2026-04-15 修回日期:2026-06-16 出版日期:2026-10-05 发布日期:2026-09-18
通讯作者: ^*luohongbo33@126.com

Distribution characteristics and influencing factors of peripheral perfusion index in intensive care unit patients

FANG Ning¹, ZHAO Mingxi¹, YUE Wenjing², LIU Xinyi³, JIANG Miao¹, FAN Liyi¹, LUO Hongbo^1*

1. Department of Critical Care Medicine; 2. Nursing Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730;
3. School of Nursing, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100144, China

Received:2026-04-15 Revised:2026-06-16 Online:2026-10-05 Published:2026-09-18
Contact: ^*luohongbo33@126.com

摘要/Abstract

摘要： 目的探讨重症监护病房患者外周灌注指数水平的分布特征及其影响因素,为临床应用提供依据。方法采用回顾性研究方法,选取2023年10月至2024年3月北京协和医院ICU收治的308例患者为研究对象。以入ICU 1 h内稳定外周灌注指数(peripheral perfusion index,PPI)均值为准,以0.6为界值,将患者分为灌注降低组与灌注正常组,比较两组临床资料,采用Logistic回归分析影响因素。结果外周灌注指数降低发生率为21.4%(66/308)。多因素Logistic回归分析显示,循环系统疾病(OR=6.956)、心率增快(OR=1.046)、PaO₂增高(OR=1.011)、机械通气(OR=3.928)和血液净化治疗(OR=23.384)是PPI降低的独立危险因素,较高的手背体温(OR=0.280)和动脉血pH值(OR=0.440)是独立保护因素(均P＜0.05)。结论外周灌注异常在重症患者中较为常见,其降低与多种临床因素相关,建议对高危患者加强PPI动态监测并综合评估,以改善患者预后。

关键词: 外周灌注指数, 重症监护病房, 危险因素, 监测

Abstract: Objective To investigate the distribution characteristics and influencing factors of peripheral perfusion index (PPI) in intensive care unit (ICU) patients. Methods A retrospective study was conducted on 308 patients admitted to the ICU of Peking Union Medical College Hospital in Beijing from October 2023 to March 2024. Based on the stable mean PPI value measured within 1 hour of admission, patients were divided into a decreased perfusion group(PPI＜0.6) and a normal perfusion group(PPI≥0.6). Results The incidence of decreased PPI was 21.4%(66/308).Multivariate logistic regression analysis showed that circulatory system diseases,increased heart rate,elevated partial pressure of oxygen(PaO₂),mechanical ventilation,and blood purification therapy were independent risk factors for a decreased PPI,while higher dorsal hand temperature and higher arterial blood pH were protective factors(all P＜0.05). Conclusions Peripheral perfusion abnormality is relatively common in critically ill patients, and decreased PPI is associated with multiple clinical factors. Dynamic PPI monitoring and comprehensive assessment are recommended for high-risk patients to improve clinical outcomes.

Key words: peripheral perfusion index, intensive care units, risk factors, monitoring

中图分类号:

R459.7

方宁, 赵明曦, 岳雯静, 柳馨怡, 姜淼, 范丽祎, 罗红波. 重症监护病房患者外周灌注指数的分布特征及影响因素分析[J]. 基础医学与临床, 2026, 46(10): 1414-1418.

FANG Ning, ZHAO Mingxi, YUE Wenjing, LIU Xinyi, JIANG Miao, FAN Liyi, LUO Hongbo. Distribution characteristics and influencing factors of peripheral perfusion index in intensive care unit patients[J]. Basic & Clinical Medicine, 2026, 46(10): 1414-1418.

参考文献

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重症监护病房患者外周灌注指数的分布特征及影响因素分析

Distribution characteristics and influencing factors of peripheral perfusion index in intensive care unit patients

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