Advances in the interaction between SNCA and GBA gene in Parkinson’s disease

Basic & Clinical Medicine ›› 2019, Vol. 39 ›› Issue (1): 97-101.

Advances in the interaction between SNCA and GBA gene in Parkinson’s disease

Received:2017-07-03 Revised:2018-01-07 Online:2019-01-05 Published:2018-12-28

Abstract

Abstract: Parkinson's disease is a neurodegenerative disease, whose cause and the mechanism is unclear. We gradually discover that genes related to PD,such as SNCA, GBA, LRRK2, SCARB2, LAMP3, BAB29/RAB7L1, MAPT, GAK, SREBF1, GPNMB, et al., increase the indicine of the sporadic PD. SNCA gene and GBA gene are the genetic factors of PD, and their interaction in PD is still illuminated.

Key words: PD, SNCA, GBA, SNCAgene, GBA gene

CLC Number:

R741.02

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Advances in the interaction between SNCA and GBA gene in Parkinson’s disease

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