Research progress in exosomes for the diagnosis and treatment of post-stroke cognitive impairment

doi:10.16352/j.issn.1001-6325.2026.06.0861

Abstract

Abstract: Exosomes can be secreted by different cells in post-stroke cognitive impairment (PSCI) and participate in the occurrence and development of PSCI by affecting the neuroinflammatory response, the blood-brain barrier, repair of damaged neurons, and reconstruction of neurovascular unit. Compared with cognitive assessment scales and traditional treatment drugs, exosomes have the advantages of early diagnosis and treatment. Exosomes can be used as new diagnostic and therapeutic targets for PSCI, providing new ideas for the diagnosis and treatment of PSCI.

Key words: exosomes;post-stroke cognitive impairment (PSCI), blood-brain barrier, neuroinflammatory reaction, engineered exosomes

CLC Number:

R741

WANG Yonghao. Research progress in exosomes for the diagnosis and treatment of post-stroke cognitive impairment[J]. Basic & Clinical Medicine, 2026, 46(6): 861-865.

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